Maverakis Lab - UC Davis
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News 74 Publications 1 Members

Limited clonality in autoimmunity: drivers and regulators.

Van Den Elzen, P Menezes, Js Ametani, A Emanual Maverakis Madakamutil, L Tang, Xl Kumar, V Sercarz, Ee

Published in Autoimmunity Reviews

The available T cell repertoire directed against self is appreciable owing to the escape of many clones from negative selection, largely because many determinants on self proteins are cryptic and not presented adequately. In addition, the degeneracy of T cell receptor specificity permits each lymphocyte a broad recognitive potential. Within the ava...

Complete regression of subcutaneous and cutaneous metastatic melanoma with high-dose intralesional interleukin 2 in comb...

Garcia, Ms Ono, Y Martinez, Sr Chen, Sl Goodarzi, H Phan, T Wehrli, Ln Miyamura, Y Fung, Ma Emanual Maverakis ...

Published in Melanoma Research

There are limited treatment options for metastatic melanoma, which is almost universally fatal. We report the successful treatment of 64 of 64 cutaneous and subcutaneous melanoma metastases in three patients using high-dose (22 million units per 1.2 ml) intralesional interleukin 2 (IL-2) in combination with topical imiquimod and a retinoid cream. B...

Age-related disparities in use of completion lymphadenectomy for melanoma sentinel lymph node metastasis.

Shah, Dr Yang, Ad Emanual Maverakis Martinez, Sr

Published in Journal of Surgical Research

Lepromatous leprosy in a 26-year-old man with concurrent disseminated tuberculosis.

Loh, E Emanual Maverakis Konia, T Noll, E

Published in Archives of Dermatology

Thymoma-associated multiorgan autoimmunity: a graft-versus-host-like disease.

Wadhera, A Emanual Maverakis Mitsiades, N Lara, Pn Fung, Ma Lynch, Pj

Published in Journal of the American Academy of Dermatology

Graft-versus-host disease (GVHD) is a T cell-mediated disease seen most commonly after hematopoietic stem cell transplantation. Rarely, a GVHD-like disease can be seen in patients with malignant thymoma. We describe a 50-year-old man with malignant thymoma who developed skin, liver, and intestinal manifestations similar to that seen in GVHD. We als...

Biosensors for immune cell analysis-A perspective. PDF available through Get Fulltext Research

Revzin, A Emanual Maverakis Chang, Hc

Published in Biomicrofluidics

Massively parallel analysis of single immune cells or small immune cell colonies for disease detection, drug screening, and antibody production represents a "killer app" for the rapidly maturing microfabrication and microfluidic technologies. In our view, microfabricated solid-phase and flow cytometry platforms of the future will be complete with b...

Sercarzian immunology—In memoriam. Eli E. Sercarz, 1934-2009.

Emanual Maverakis

Published in Cellular Immunology

During his long career as a principal investigator and educator, Eli Sercarz trained over 100 scientists. He is best known for developing hen egg white lysozyme (HEL) as a model antigen for immunologic studies. Working in his model system Eli furthered our understanding of antigen processing and immunologic tolerance. His work established important...

Eruptive keloids associated with breast cancer: a paraneoplastic phenomenon?

He, Y Merin, Mr Sharon, Vr Emanual Maverakis

Published in Acta Dermato Venereologica

Effective Strategies for the Management of Pyoderma Gangrenosum.

Goodarzi, H Sivamani, Rk Garcia, Ms Wehrli, Ln Craven, H Ono, Y Emanual Maverakis

Published in Advances in Wound Care

Effective strategies for the management of pyoderma gangrenosum: a comprehensive review.

Patel, F Fitzmaurice, S Duong, C He, Y Fergus, J Raychaudhuri, Sp Garcia, Ms Emanual Maverakis

Published in Acta Dermato Venereologica

Pyoderma gangrenosum (PG) is an inflammatory disease characterized by painful skin ulcerations with undermined and erythematous borders. The etiology of PG is not well understood, but it is generally considered to be an aberrant immune response characterized by a dermal neutrophilc infiltrate. Given the existence of only a few PG clinical trials, t...

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